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Piroxicam Betacyclodextrine manufacturers India – Taj Pharmaceuticals exporter Cas No.- 96684-40-1 Piroxicam Betacyclodextrine suppliers from india companies Pharmaceuticals Piroxicam Betacyclodextrine manufacturers India definition of Piroxicam Betacyclodextrine Piroxicam Betacyclodextrine synthesis Piroxicam Betacyclodextrine salt effects of Piroxicam Betacyclodextrine clinical advantage of Piroxicam Betacyclodextrine polymorphs of Piroxicam Betacyclodextrine preparation of Piroxicam Betacyclodextrine efficacy of Piroxicam Betacyclodextrine beneficial effects of Piroxicam Betacyclodextrine determination and validation of Piroxicam Betacyclodextrine determination Piroxicam Betacyclodextrine Piroxicam Betacyclodextrine Piroxicam Betacyclodextrine side effect of Piroxicam Betacyclodextrine polymorphs of Piroxicam Betacyclodextrine level of Piroxicam Betacyclodextrine Piroxicam Betacyclodextrine process for preparing Piroxicam Betacyclodextrine abeprazole Sodium mg process for Piroxicam Betacyclodextrine detailed info for Piroxicam Betacyclodextrine catalog Purchase Cheap Lowest Price COA MSDS certificate of Analysis wholesalers india Piroxicam Betacyclodextrine suppliers india Piroxicam Betacyclodextrine trader Drug india Piroxicam Betacyclodextrine purchase india Piroxicam Betacyclodextrine structure Piroxicam Betacyclodextrine benefits Piroxicam Betacyclodextrine pharmacy and drugs industries in India indian chemical company chemical factories india safety Piroxicam Betacyclodextrine manufacturers India plastic

 

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Piroxicam Betacyclodextrine CAS Registry Number 96684-40-1

Molecular Structure

Piroxicam Betacyclodextrine Molecular Formula C20H21N3O7S

Piroxicam Betacyclodextrine

Molecular Formula C20H21N3O7S

Molecular Weight 447.46

CAS Registry Number
96684-40-1

Piroxicam-beta-cyclodextrin is a complex of the established nonsteroidal antiinflammatory drug (NSAID) piroxicam and an inert cyclic macromolecule, beta-cyclodextrin. In clinical trials in patients with rheumatic diseases or pain arising from other conditions, it was as effective an analgesic as standard piroxicam, and showed a faster onset of action on the first day of treatment. In short term pharmacodynamic studies in healthy volunteers, piroxicam-beta-cyclodextrin was equivalent to or tended to show less gastrointestinal mucosal toxicity than standard piroxicam, as assessed by endoscopy and faecal blood loss. However, no data are available on its comparative gastrointestinal mucosal effects from long term clinical trials using similar measures. Preliminary findings from a clinical study suggest piroxicam-beta-cyclodextrin caused fewer gastroduodenal lesions than tenoxicam. As with other NSAIDs, the majority of adverse events associated with piroxicam-beta-cyclodextrin in clinical trials were gastrointestinal in origin, with epigastric pain, heartburn and nausea the most common. Thus, piroxicam-beta-cyclodextrin is an effective agent in patients with rheumatic diseases or other pain states. When rapid analgesia is required in the initial treatment of acute pain, the faster onset of action of piroxicam-beta-cyclodextrin may be an advantage over the parent compound; however, this is unlikely to be important during long term therapy. The results of further long term trials are awaited before firm conclusions can be reached regarding the gastrointestinal tolerability of piroxicam-beta-cyclodextrin compared with that of standard piroxicam and other NSAIDs.
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